Biosensors: Recent advances and mathematical challenges


Johann F. Osma
University of Los Andes
Margarita Stoytcheva
Autonomous University of Baja California

Many researchers and research groups around the globe are dealing with interdisciplinary problems and multidisciplinary groups; but especially those that deal everyday with biosensors have the feeling of not having enough personnel with the sufficient background to cover all topics. With this feeling in our minds, we decided to invite wonderful researchers from different parts to design this book, not as a conventional biosensor’s book, but as an interesting journey in the complex world of biosensors. A close look to some recent and key advances on the topic, but at the same time tips through novel mathematical modelling to improve our work, and last but not least, tricks to fool those undesired electrical  disturbances that commonly messes our daily work can be found in these pages.
Feel free to navigate the book through its chapters, once in your hands you will feel eager to learn more about biosensors. It has been an experience to put all this together; but now, with the book ready, we can say that this trip has being a wonderful adventure. That is why want to thank all the authors for their great contributions.


  • Prologue and Introduction
    Johann F. Osma, Margarita Stoytcheva
  • Use of functional metalic nanostructures in biosensors
    Rukan Genc
  • Bacterial membrane formation monitored with atomic force microscopy and quartz crystal microbalance
    Nadja Krska, Jose L. Toca-Herrera
  • Whole cell biosensors
    César A. Hernández, Johann F. Osma
  • Electrochemical biosensors for the detection of microcystins
    Recent advances and perspectives
    Audrey Sassolas, Akhtar Hayat, Jean-Louis Marty
  • Phenolic compounds determination in water by enzymatic-based electrochemical biosensors
    Juan C. Gonzalez-Rivera, Jorge E. Preciado, Johann F. Osma
  • Electrochemical detection of dopamine using graphite electrodes modified with PAMAM G4.0-64OH dendrimers in synthetic cerebrospinal fluids
    G. Armendariz, J. Manríquez, A. Santamaría, A. Herrera-Gómez, E. Bustos
  • Continuous monitoring based on biosensors coupled with artificial intelligence
    Rocío B. Domínguez Cruz, Gustavo A. Alonso, Roberto Muñoz, Jean-Louis Marty
  • Modeling a second-generation glucose oxidase biosensor with statistical machine learning methods
    Livier Rentería-Gutiérrez, Lluís A. Belanche-Muñoz, Félix F. González-Navarro, Margarita Stoytcheva
  • Modeling the influence of pH and temperature on the response of an acetylcholinesterase biosensor using machine learning methods
    Edwin R. García Curiel, Larysa Burtseva, Margarita Stoytcheva, Félix F. González-Navarro, Ana Sofia Estrella Sato
  • Digital analysis and treatment for electromagnetic disturbances in biomedical instrumentation
    Javier Enrique Gonzalez Barajas, Davis Montenegro
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