Immunotoxic Gluten Fraction Detection: Applications in Food Safety

Isabel Comino Montilla, Ana Real, María de Lourdes Moreno, Carolina Sousa

Resumen


The only currently available therapy for celiac patients is a life-long strict gluten-free diet, however, it generates numerous social and economic repercussions. Various studies have suggested that failure to comply with the diet is frequent in celiac patients. For this reason, and because of the currently recognized importance of nutrition in the management of CD, the development of new strategies for monitoring the gluten-free diet is essential. In this sense, for celiac patients, the toxicity of cereals such as oats is questioned. Studies have shown that oat’s immunogenicity depends on interindividual sensitivity and the cultivar used. The incorporation of harmless oat varieties in food products may improve the nutritional quality of the gluten-free diet. Additionally in the search for a less-toxic barley, it has been demonstrated that cultivated varieties contain lower levels of immunogenic gluten than the wild ones. This fact is important in breeding programs of cultivated species and in the preparation of certain foods and beverages derived from toxic cereals.

Palabras clave


celiac, immunotoxic gluten, food safety

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